Custom Enzymes and Inhibitors
Selleck Chemical LLC Temsirolimus (CCI-779) 10mg 162635-04-3 NSC 683864
Temsirolimus (CCI-779, NSC 683864) is a specific mTOR inhibitor with IC50 of 1.76 ?M in a cell-free assay. Temsirolimus induces autophagy and apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Ubiquitin aldehyde (recombinant) (50 µg)
High purity inhibitor of deubiquitinylating enzymes (DUBs). Synthetically modified recombinant ubiquitin. The modification of the C-terminal glycine carboxyl into an aldehyde results in a potent, highly specific inhibitor of all ubiquitin deconjugating enzymes, including ubiquitin C-terminal hydrolases (UCHs), ubiquitin-specific proteases (USPs) and deubiquitinylating enzymes (DUBs). Alternative name: Ub-H. MW: 8.5kDa. Purity: ≥95% (HPLC). Sequence Recombinant Ubiquitin (corresponding to UniProt sequence P62988). The C-terminal glycine carboxyl is synthetically modified to an aldehyde. Formulation: Liquid. In aqueous solution containing 0.15M HCl. Source: Produced in E.coli. UniProt: P0CG47 (UBB), P0CG48 (UBC), P62979 (RPS27A), P62987 (UBA52). Handling: Do not neutralise until immediateley prior to use. Do not lyophilize. Avoid presence of amino-containing compounds. Soluble and stable in aqueous solution at pH <7.0. Long Term Storage: +4°C
Meridian Life Science Tru Block, 0.1 g
HAMA Blocker against Immunoassay Interference - actively blocks Heterophilic Antibody (HA) interference in immunoassays including, but not limited to, Human Anti-Mouse Antibody (HAMA) interference.
Chemie Tek PI3K INHIBITOR
BYL179 is an orally bioavailable, next generation PI3K alpha - isoform specific inhibitor, currently in clinical trials.
Selleck Chemical LLC Gefitinib (ZD1839) 250mg 184475-35-2 Iressa
Gefitinib (ZD-1839, Iressa) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. Gefitinib promotes autophagy and apoptosis of lung cancer cells via blockade of the PI3K/AKT/mTOR pathway. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Epigentek Inc EpiQuik DNMT Activity/Inhibition Assay Ultra Kit (Colorimetric) (96 assays)
For absorbance-based measurement of DNA methyltransferase activity or inhibition
Selleck Chemical LLC MLN8054 5mg 869363-13-3
MLN8054 is a potent and selective inhibitor of Aurora A with IC50 of 4 nM in Sf9 insect cell. It is more than 40-fold selective for Aurora A than Aurora B. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences K 858 >=98% (HPLC) | 72926-24-0 | MFCD00181155 | 25MG
K 858 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 277.34 | 72926-24-0 | MFCD00181155 | 25MG
Bioworld Pectinase, 1 g
Pectinase Also known as Poly-(1,4-a-D-galacturonide)glycanohydrolase. Used in plant protoplast preparation to digest cell wall prior to organelle isolation.
Medchemexpress LLC HY-103353 5mg Medchemexpress, SID 26681509 CAS:958772-66-2 Purity:>98%
Medchemexpress, HY-103353 5mg SID 26681509 CAS:958772-66-2 SID 26681509 is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM. SID 26681509 inhibits in vitro propagation of malaria parasite Plasmodium falciparum and inhibits Leishmania major with IC50s of 15.4 μM and 12.5 μM, respectively. SID 26681509 shows no inhibitory activity against cathepsin G. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-107613 10mg Medchemexpress, R 59-022 CAS:93076-89-2 Purity:>98%
Medchemexpress, HY-107613 10mg R 59-022 CAS:93076-89-2 R 59-022 (DKGI-I) is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 is a 5-HTR antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[3][4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Organic Chemistry trans-2-Phenylcyclopropyl isocyanate | 5G | 63009-74-5 | MFCD00001273
CAS #: 63009-74-5
MDL #: MFCD00001273
Purity: >90%
UNSPSC Code: 12352100
Molecular Weight: 159.18